Diabetes elevates the risk of various cancers development

Emobileclinic Researchers’corner

So many studies have established the link between diabetes type 2 and cancers. It is believed that people with diabetes have an approximately 20–25% higher cancer incidence compared with persons without diabetes, though this varies by cancer site says Dr.Vigneri P in his research ”Diabetes and cancer”. According to him, being diabetes is a risk factor to several cancers.

”Epidemiological studies clearly indicate that the risk of several types of cancer (including pancreas, liver, breast, colorectal, urinary tract, and female reproductive organs) is increased in diabetic patients,” This also increased mortality rate in this regard. The association between type 2 diabetes and some types of cancer is well established and the complexity of this association is receiving increasing recognition. Many factors influence the risk of both diabetes and cancer including age, sex, ethnicity, socioeconomic status, obesity/insulin resistance, diet (including alcohol intake), physical activity levels and smoking history.



The latest research says type 1 diabetes is linked to an increased rate of various cancers and decreases certain risk of cancers.

According to Sarah Wild, Ph.D., professor of epidemiology at the University of Edinburgh in the United Kingdom, type 1 diabetes increases certain cancer risk in both male and female. She observed 9149 diabetes type 1 cases in 5 countries and came up with the results that both male and female with diabetes type 1 have higher risk of liver pancreas,kidney and stomach cancer. She however noted that women with type 1 diabetes had elevated risk of esophagus, endometrium,ovary and thyroid cancer. This influence was noticed to reduce women’ s risk for melanoma, breast cancer and Hodgkin’s lymphoma.
The researchers also observed that ”among men with type 1 diabetes, elevated risks were observed for colon cancer and non-Hodgkin’s lymphoma. Men with type 1 diabetes had a 44% lower incidence of prostate cancer than that observed in the general population. In addition, we found a borderline significant 12% lower risk of testis cancer in men with type 1 diabetes”

Further considering the link between diabetes and cancer Dr Smith U, Gale EAM ,believes the association has to do with the treatment therapy. ”The observed excess risk of cancer in persons with diabetes may, to some extent, be a consequence of anti-diabetic drug therapies, such as exogenous insulin ,” he says. There is some evidence that insulin-treated patients have a higher cancer incidence compared with non-insulin-treated patients and Dr. Carstensene of Steno Diabetes Center,believes if insulin use is associated with increased cancer risk, then an excess risk of cancer should be apparent in persons with type 1 diabetes, and this excess risk could potentially be larger than that observed in persons with type 2 diabetes”. The effect of insulin drugs on sprouting cancers have been a debating issues for some times and call for various alternative medicines with lesser effects on diabetes patients.

Sources
1.Springer.com
2.PubMed