Causes & Symptoms of Pemphigoid

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Pemphigoid is an uncommon autoimmune disorder characterized with the malfunctioning of the immune system resulting in skin rashes and blistering on the arms, abdomen and the legs. It can manifest at any age and condition especially during pregnancy. It must be emphasized that no permanent cure exists for pemphigoid, it can only be managed with appropriate treatment.

There are basically three types of pemphigoid, they are:

Bullous Pemphigoid: a condition when the blistering of the skin happens in the movement areas of the body such as the arms, legs, joints and lower abdomen. It is the most common of the three types.

Cicatricial Pemphigoid: the blister and rash occur on the mouth, eyes, nose, throat and the genitals. It easily spread to other parts of the mucous areas if left untreated.

Pemphigoid Gestationis: this type is associated with pregnancy which can happen during and immediately after delivery. It mostly developed in the second and third trimester of pregnancy. The rash usually forms on the legs, abdomen and the arms.


Autoimmune disease
Allergic reaction to medication
Allergic reaction to radiation therapy
Ultraviolet light therapy.


Blister formation on the arms, legs, abdomen and mucous membranes
Painful ruptured blister
Reddish rash


A Dermatologist after a close physical examination of the blister will be able to request for an appropriate diagnostic measure.
Consequently, the doctor may be ordered for a biopsy to test the sample for the immune system antibodies features of pemphigoid.


Using of various medications to reduce the inflammation, ease the itch, and heal the blister.

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Medication may also be taken by suppressing the immune system.

Using antibiotics such as tetracycline to lower inflammation and treat the infection.

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