Causes and symptoms of white bloods cell presence in the urine

 

 

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The Leukocytes also known as white blood cell is part of the immune system which play significant role in the body; they offer protection for the body against any infectious disease and any foreign bodies. They are produced and domiciled in all parts of the body including the spleen, bone marrow and the thymus with the view to fighting any infection that may cause problem.
It is not necessarily abnormal to find little amount of white blood cell in the urine, it becomes worrisome when the urine contains high levels of white blood cells as this may suggest a serious underlying medical problems.
Causes
The following are some of the causes of white blood cells in the urine:
Urinary tract infection
Kidney stones
Infection in the kidney
Obstruction within the urinary system
Pregnancy
Prolong stay of urine in the bladder
Sickle cell anemia
Certain cancers particularly prostate, bladder or kidney cancer
Engaging in strenuous

 

 

Symptoms
Incessant urination
Offensive urine
Stomach discomfort
Nausea
Fever
Vomiting
Painful sexual intercourse

 
Diagnosis

After consulting with the medical doctor, the following tests can be ordered to diagnose the condition.
Urinalysis remains the main diagnostic method. This can be done using dipstick method, visual and microscopic examination.

 
Treatment
The following are the available treatment options:
Using of appropriate antibiotic drugs especially in cases of urinary tract infection.
Using of appropriate pain relieving medication may also be taken to lessen the accompanied pains.
Special care more be provided by top medical officer in pregnant women and people with serious cancer.
Change in lifestyle may also be effective in managing cases affecting the kidney.

Prostate Massage Therapy

One of the most common cancers affecting male is prostate cancer. It is the leading common urinary tract infection in male across all age group. The prostate is a vital component of the male reproductive system which secretes prostatic fluid needed in the semen to enhance male fertility.

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It is located deep in the male body below the bladder, surrounded by the urethra and in front of the rectum.

The convention means of diagnosing prostate cancer in the use of a digital rectal examination to examine the extent of the inflammation of the prostate.

It is generally believe that prostate massage therapy offers great relieve and management of prostate cancer known as prostatitis.

 
Symptoms
Erectile dysfunction
Burning ejaculation
Incessant urination
Difficulty in urinating
Painful urination
Presence of blood in urine
Fever
Back and muscular pain
Causes
Bacterial infection
Nonbacterial microorganisms
Damaged or injured nerve
Immune system disorder
Treatment is usually with medications such as antibiotics and muscle relaxants, depending on the cause. These treatments are effective for many patients, but not all.
Prostate massage
A prostate massage is a digital rectal examination done by medical doctor to examine the condition and the entire size of the prostate gland to check for lumps and other harmful signs that may cause any health problems.
The prostate massage is performed by insertion a finger under glove into the rectum of the patient with a view to press the surrounding prostate. In the event that there is an infection, the doctor will massage or rub the prostate to collect fluid known as prostatic secretion for further investigation which is aimed at determining the evidence of infection and inflammation.

 
Benefits

Enhancement of sexual experience
Averts the formation of prostatic fluid in the prostate
Minimization of associated discomfort of a swollen prostate
Compliment the effectiveness of antibiotics use in managing prostatitis
Enhances healthy prostate functioning
Improves and possibly sustains erection
Allows for harmless and easy urination

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Possible Complications

Deteriorate acute prostatitis
Blood poisoning resulting from infection
Bleeding within the prostate
Rectal lining damage
Cellulitis
Hemorrhoids flare-ups
Spread of prostate cancer if present before the massage
Safety tips
Minimal pressure must be applied on the prostate so as to avoid likely damage to the rectal lining.
It is also important to maintain good and proper hygiene while on the therapy to avoid infection.
The area is very sensitive, so any intervention must be carried out with caution and proper hygiene.
Study says that restoring flawed tumor blood vessels could offer better cancer treatments

The Journal of Cancer Cell has published the findings of researchers led by Dr Peter Carmeliet who discovered a new way to normalize the dysfunctional blood vessels that are typical for tumors. According to them, those vessels has significant role in cancer metastasis, as their fragility and permeability enables cancer cells to pass through the blood stream and fight other organs.

The researchers were able to reduce the actions of these cancers by manipulating the blood vessel cells’ sugar metabolism which enables them to establish a healthy and structured blood vessel network. Apart from averting the spread of cancer cells, the restored vessels produced chemotherapy drugs in a more efficient way to the tumor.
Blood vessel cells also known as endothelial cells, in tumors have to divide quickly and hence need large quantities of sugar. As a result, the metabolism of those cells become overheated, which in turn render them fragile, dysfunctional and irregular in shape and size. As a result of the weaknesses of flawed vessels, cancer cells use them as a platform to proliferate to far organs. Furthermore, they are unable to provide adequate oxygen for the tumor, which enables the tumor to spread even further. Lastly, poorly-functioning vessels impede the smooth delivery of chemo- and immunotherapy drugs to the tumor.

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In contrast to the traditional cancer therapy aimed at obstructing new blood vessel tumor emergence and destroying existing tumor vessels, the research team led by Professor Peter Carmeliet (VIB-KU Leuven) focused on normalizing the inimical process instead.

According to the team leader, “therapies that destroy tumor vessels are not always effective. In some cases, patients even show resistance to these drugs. So when we investigated the root of the problem, we were pleased to see that dysfunctional vessels are very susceptible to drugs blocking their sugar metabolisms, precisely because their sugar engines are so overheated. Our study proves that we could neutralize this out-of-control sugar consumption with a small molecule compound, thereby healing the impaired tumor vessels.”

Apart from minimizing the probability of cancer cells proliferation of the entire body, a future vessel normalization therapy has other perks as well. As a matter of fact, it offers not only improved chemotherapy standard but also created an extra benefits to recently developed immunotherapy.

The team leader further said: “our study also shows that healthy tumor vessels ensure a better delivery of chemotherapeutic agents to the tumor. In addition, they could improve the supply of immune cells as well. This is very important, because many emerging cancer therapies directly address the body’s immune system. That is why we are already planning to investigate the effects of tumor vessel normalization therapy with immunotherapy. In this way, we are getting closer to identifying more targeted and specific treatments in the fight against cancer.”

 

 

 

 

Source

Cantelmo, A. R et.al (2016): Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy. Cancer Cell, doi: 10.1016/j.ccell.2016.10.006



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